POLY(2-METHACRYLOYLOXYETHYLPHOSPHORYLCHOLINE-BB-2-UREIDOETHYLMETHACRYLATE)COPOLYMER AND POLYMER MICELLE FORMED WITH THE SAME

摘要

PROBLEM TO BE SOLVED: To provide an upper limit critical consolute temperature type (UCST type) temperature-responsive polymer compound having biological functions which responds to the temperature in water or under a physiological condition and its various applications as a temperature-responsive material.SOLUTION: Poly(2-methacryloyloxyethylphosphorylcholine-b-2-ureidoethylmethacrylate) diblock copolymer obtained by modifying poly(2-methacryloyloxyethylphosphorylcholine-2-aminoethylmethacrylate) diblock copolymer serves as a temperature-responsive material. A polymer micelle formed with the copolymer in water or under a physiological condition is also provided.