发明名称 |
USE OF AN ION EXCHANGE MEMBRANE TO REMOVE IMPURITIES FROM CELL -BINDING AGENT CYTOTOXIC AGENT CONJUGATES |
摘要 |
<p>The invention provides processes for preparing purified cell- binding agent cytotoxic agent conjugates comprising subjecting a mixture comprising a cell- binding agent cytotoxic agent conjugate and one or more impurities to an ion exchange chromatography membrane to remove at least a portion of the impurities from the mixture, thereby providing a purified cell- binding agent cytotoxic agent conjugate.</p> |
申请公布号 |
IN3203DEN2015(A) |
申请公布日期 |
2015.10.02 |
申请号 |
IN2015DE03203 |
申请日期 |
2015.04.16 |
申请人 |
IMMUNOGEN, INC. |
发明人 |
LI ,XINFANG;CHENG ,WENJIE |
分类号 |
A23J1/10;A61K47/48;C07K16/46 |
主分类号 |
A23J1/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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