EFFICIENT HIGH YIELD CONVERSION OF MONOSACCHARIDES TO 5 (CHLOROMETHYL) 2 FURALDEHYDE

摘要

The present invention describes methods and apparatuses for the synthesis of 5 (chloromethyl) 2 furaldehyde (CMF) from monosaccharides the method comprising: (a) contacting monosaccharides hydrochloric acid and an organic solvent by way of a continuous biphasic flow reactor assembly at a temperature from about 60 degree C to about 200 degree C and pressures from about 1 atm to 10 atm such that CMF is produced; (b) separating 5 (chloromethyl) 2 furaldehyde by liquid/liquid and solid/liquid phase separation; (c) producing at least five kilograms per day with at least 50% yield.