| 发明名称 |
METHODS AND COMPOSITIONS FOR TREATMENT OF HEMATOLOGIC CANCERS |
| 摘要 |
The present invention relates to oncolytic Picornaviruses and methods and compositions for treating subjects having hematologic cancers. These include methods and compositions for treatment of myeloma, using disclosed Picornavirus such as Coxsackievirus, in methods of direct or indirect administration to subjects and ex vivo purging of malignant cells within auto grafts prior to transplantation. |
| 申请公布号 |
US2015273002(A1) |
申请公布日期 |
2015.10.01 |
| 申请号 |
US201414579826 |
申请日期 |
2014.12.22 |
| 申请人 |
Viralytics Limited |
发明人 |
Au Gough Geoffrey;Shafren Darren Raymond |
| 分类号 |
A61K35/768;C12N7/00;A61K45/06 |
主分类号 |
A61K35/768 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating and/or preventing hematologic cancer in a subject, the method comprising administering a therapeutically effective amount of a Picornavirus or a modified form thereof such that at least some cells of the cancer undergo viral oncolysis. |
| 地址 |
North Ryde AU |
