发明名称 |
TYROSINE KINASE INHIBITORS FOR USE IN A METHOD OF TREATING CANCER IN ASSOCIATION WITH A REDUCED CALORIC INTAKE |
摘要 |
A tyrosine kinase inhibitor (TKI) for use in a method for the treatment of cancer in a patient, wherein the method comprises subjecting the patient to reduced caloric intake, i.e a daily caloric intake reduced by 10-100%, including starvation, for a period of 24-190 hours and administering the tyrosine kinase inhibitorto the patient during such period; the tyrosine kinase inhibitor is preferably selected among Lapatinib, Crizotinib, Gefitinib, Erlotinib, Afatinib and Regorafenib. |
申请公布号 |
CA2944088(A1) |
申请公布日期 |
2015.10.01 |
申请号 |
CA20152944088 |
申请日期 |
2015.03.30 |
申请人 |
L-NUTRA INC.;UNIVERSITA DEGLI STUDI DI GENOVA |
发明人 |
BALLESTRERO, ALBERTO;CAFFA, IRENE;LONGO, VALTER;NENCIONI, ALESSIO;ODETTI, PATRIZIO;PATRONE, FRANCO |
分类号 |
A61K31/517;A61K31/44;A61K31/4439;A61K31/506;A61P35/00 |
主分类号 |
A61K31/517 |
代理机构 |
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代理人 |
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地址 |
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