摘要 |
The present invention is directed to a bicyclic heteroaryl benzamide compounds of formula(I) which are tropomyosin-related kinase(Trk)family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF)receptor TrkA. |
申请人 |
MERCK SHARP & DOHME CORP.;MITCHELL, HELEN;FRALEY, MARK E.;COOKE, ANDREW J.;STUMP, CRAIG A.;BESHORE, DOUGLAS C.;MCCOMAS, CASEY C.;SCHIRRIPA, KATHY;ZHANG, XU-FANG;MCWHERTER, MELODY;MERCER, SWATI P.;MOORE, KEITH;LIU, CHUNGSING;MAO, QINGHAU |
发明人 |
MITCHELL, HELEN;FRALEY, MARK E.;COOKE, ANDREW J.;STUMP, CRAIG A.;BESHORE, DOUGLAS C.;MCCOMAS, CASEY C.;SCHIRRIPA, KATHY;ZHANG, XU-FANG;MCWHERTER, MELODY;MERCER, SWATI P.;MOORE, KEITH;LIU, CHUNGSING;MAO, QINGHAU |