发明名称 TrkA KINASE INHIBITORS,COMPOSITIONS AND METHODS THEREOF
摘要 The present invention is directed to a bicyclic heteroaryl benzamide compounds of formula(I) which are tropomyosin-related kinase(Trk)family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF)receptor TrkA.
申请公布号 WO2015143652(A1) 申请公布日期 2015.10.01
申请号 WO2014CN74143 申请日期 2014.03.26
申请人 MERCK SHARP & DOHME CORP.;MITCHELL, HELEN;FRALEY, MARK E.;COOKE, ANDREW J.;STUMP, CRAIG A.;BESHORE, DOUGLAS C.;MCCOMAS, CASEY C.;SCHIRRIPA, KATHY;ZHANG, XU-FANG;MCWHERTER, MELODY;MERCER, SWATI P.;MOORE, KEITH;LIU, CHUNGSING;MAO, QINGHAU 发明人 MITCHELL, HELEN;FRALEY, MARK E.;COOKE, ANDREW J.;STUMP, CRAIG A.;BESHORE, DOUGLAS C.;MCCOMAS, CASEY C.;SCHIRRIPA, KATHY;ZHANG, XU-FANG;MCWHERTER, MELODY;MERCER, SWATI P.;MOORE, KEITH;LIU, CHUNGSING;MAO, QINGHAU
分类号 C07D235/00;A61K31/16;A61P29/00;C07D263/52;C07D275/04;C07D277/60;C07D285/14;C07D291/08 主分类号 C07D235/00
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