发明名称 |
MONOCLONAL ANTIBODIES TO GROWTH AND DIFFERENTIATION FACTOR 15 (GDF-15), AND USES THEREOF FOR TREATING CANCER CACHEXIA AND CANCER |
摘要 |
<p>The present invention relates to monoclonal anti-human-GDF-15 antibodies. The antibodies include chimeric antibodies and humanized antibodies. The invention also relates to monoclonal anti-human-GDF-15 antibodies including murine antibodies, chimeric antibodies and humanized antibodies for use in methods for the treatment of cancer cachexia and also for the treatment of cancer. The invention also provides pharmaceutical compositions, kits, methods and uses and cell lines capable of producing the monoclonal antibodies of the invention.</p> |
申请公布号 |
WO2015144855(A1) |
申请公布日期 |
2015.10.01 |
申请号 |
WO2015EP56654 |
申请日期 |
2015.03.26 |
申请人 |
JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG |
发明人 |
WISCHHUSEN, JÖRG;JUNKER, MARKUS;SCHÄFER, TINA;PÜHRINGER, DIRK |
分类号 |
C07K16/22 |
主分类号 |
C07K16/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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