摘要 |
PROBLEM TO BE SOLVED: To provide an aqueous pharmaceutical formulation that comprises high-unit insulin glargine, equivalent in exposure and activity to a formulation of insulin glargine 100U, and a method of treating Type I and Type II Diabetes Mellitus of a patient using the same.SOLUTION: The application relates to an aqueous pharmaceutical formulation comprising 200-1000 U/mL [equimolar to 200-1000 IU human insulin] of insulin glargine, with the proviso that the insulin glargine concentration of the formulation is not 684 U/mL, and its use. |