发明名称 |
METHOD OF MANUFACTURING FINE PARTICLES SUITABLE FOR ORALLY DISINTEGRATING PHARMACEUTICAL DOSAGE FORMS |
摘要 |
Disclosed are methods of making oral pharmaceutical compositions that contain substantially crush resistant drug containing microparticles. The microparticles may contain an active pharmaceutical agent, a polymer and a plasticizer. The microparticles may be uncoated (so as to impart an immediate release profile) or coated so as to impart an extended release (ER), delayed release (DR) or delayed extended release (DER) profile. One or more of the populations of microparticles may be coated with a taste masking composition. The methods may produce oral compositions such as orally disintegrating tablets that contain one or more these types of microparticles in order to further customize the release profile. Also disclosed are the oral compositions, per se, and methods of using same for their intended purposes. |
申请公布号 |
WO2015148538(A1) |
申请公布日期 |
2015.10.01 |
申请号 |
WO2015US22289 |
申请日期 |
2015.03.24 |
申请人 |
KASHIV PHARMA, LLC |
发明人 |
VAKA, SIVA RAM KIRAN;DESAI, DIPEN;PHUAPRADIT, WANTANEE;SHAH, NAVNIT H.;MEGHPARA, KANJI |
分类号 |
A61K9/20;A61K9/22;A61K9/28;A61K9/32 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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