MITOCHONDRIAL MARKERS OF NEURODEGENERATIVE DISEASES

摘要

The invention relates to an in vitro method for diagnosing or determining the risk of a subject developing a neurodegenerative disease based on the determination of the methylation pattern in certain regions of the mitochondrial DNA of said subject or based on the determination of the nucleotide in the polymorphic position 16519 of the mitochondrial DNA of said subject. The invention further relates to nucleic acids suitable for implementing the invention.