| 发明名称 |
VACCINE |
| 摘要 |
The present invention relates to the field of vaccines for protecting against polio, and in particular to combination vaccines for protecting against polio, diphtheria, tetanus, and pertussis diseases. Specifically, vaccines comprising reduced dose inactivated poliovirus (IPV) is provided, which can maintain an adequate or improved level of protection against polio. |
| 申请公布号 |
US2015273047(A1) |
申请公布日期 |
2015.10.01 |
| 申请号 |
US201414579353 |
申请日期 |
2014.12.22 |
| 申请人 |
DE HEMPTINNE HERVE;DUCHENE MICHEL;MARY ANNE;SONVEAUX MARC |
发明人 |
DE HEMPTINNE HERVE;DUCHENE MICHEL;MARY ANNE;SONVEAUX MARC |
| 分类号 |
A61K39/13;A61K39/102;A61K39/29;A61K39/385;A61K39/00 |
主分类号 |
A61K39/13 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An inactivated poliovirus (IPV) vaccine comprising:
(a) diphtheria toxoid; (b) tetanus toxoid; (c) killed whole-cell Bordetella pertussis, substantially thiomersal free; or two or more acellular pertussis components (Pa), and; (d) inactivated poliovirus type 1, type 2 and type 3, wherein: the inactivated poliovirus type 1 is present at a dose greater than 10 D-antigen units and less than 20 D-antigen units; the inactivated poliovirus type 2 is present at a dose of 2-4 D-antigen units; and the inactivated poliovirus type 3 is present at a dose of 8-20 D-antigen units. |
| 地址 |
Rixensart BE |
