发明名称 |
RESOLUBILIZATION OF PROTEIN CRYSTALS AT LOW PH |
摘要 |
A method for purifying a protein product prepared in a fermentation process where the protein of interest is present in solid, crystalline or amorphous form in the fermentation container is disclosed, where the pH of the fermentation broth is adjusted to a low pH whereby the protein of interest dissolves and can be efficiently separated from insoluble. |
申请公布号 |
WO2015144936(A1) |
申请公布日期 |
2015.10.01 |
申请号 |
WO2015EP56921 |
申请日期 |
2015.03.30 |
申请人 |
NOVOZYMES A/S |
发明人 |
PEDERSEN, POUL ERIK;PERSSON, JON MARTIN;FRIIS, ESBEN PETER |
分类号 |
C07K1/00;C07K1/14 |
主分类号 |
C07K1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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