MITOCHONDRIAL MARKERS OF NEURODEGENERATIVE DISEASES
摘要
The invention relates to an in vitro method for diagnosing or determining the risk of a subject developing a neurodegenerative disease based on the determination of the methylation pattern in certain regions of the mitochondrial DNA of said subject or based on the determination of the nucleotide in the polymorphic position 16519 of the mitochondrial DNA of said subject. The invention further relates to nucleic acids suitable for implementing the invention.
申请公布号
WO2015144964(A2)
申请公布日期
2015.10.01
申请号
WO2015ES70230
申请日期
2015.03.27
申请人
INSTITUT D'INVESTIGACIÓ BIOMÈDICA DE BELLVITGE (IDIBELL);UNIVERSITAT DE BARCELONA
发明人
BARRACHINA CASTILLO, MARTA;FERRER ABIZANDA, ISIDRE;BLANCH LOZANO, MARTA