Cylindrical Multi-Reflecting Time-of-Flight Mass Spectrometer

摘要

A method and apparatus are disclosed for improving resolution and duty-cycle of a multi-reflecting TOF mass spectrometer (MR-TOF) by arranging a cylindrical analyzer having an appropriate radial deflection means, means for limiting ion divergence in the tangential direction and a pulsed source providing ion packet divergence of less than 1 mm*deg. There are disclosed embodiments for fifth-order focusing cylindrical ion minors. Separate embodiments provide parallel tandem MS-MS within a single cylindrical MR-TOF.

主权项

1. A multi-reflecting time-of-flight mass spectrometer comprising:
a pulsed ion source or a pulsed converter; at least two parallel electrostatic ion minors having a field-free region spaced there between, wherein each of said ion minors has at least one electrode with attracting potential, and wherein each of the ion minors is made of a ring cap electrode and two sets of coaxial ring electrodes to form a cylindrical volume between outer and inner electrode sets, and further wherein a mean radius of the cylindrical volume is larger than one sixth of distance between mirror caps, and even further wherein one of said ion minors or said field free space comprises at least one ring electrode for radial ion deflection; means for limiting ion divergence in the tangential direction; and a pulsed ion source or a pulsed converter for generating ion packets with the phase space in the tangential direction of less than 1 mm*deg.