| 发明名称 |
Broadly-Neutralizing Anti-HIV Antibodies |
| 摘要 |
The present invention relates to anti-HIV antibodies. Also disclosed are related methods and compositions. HIV causes acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies. Since its discovery in 1981, HIV type 1 (HIV-1) has led to the death of at least 25 million people worldwide. |
| 申请公布号 |
US2015274813(A1) |
申请公布日期 |
2015.10.01 |
| 申请号 |
US201314436608 |
申请日期 |
2013.10.18 |
| 申请人 |
THE ROCKEFELLER UNIVERSITY ;CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
Mouquet Hugo;Nussenzweig Michel;Bjorkman Pamela J.;Scharf Louise |
| 分类号 |
C07K16/10;A61K45/06;A61K39/42 |
主分类号 |
C07K16/10 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. An isolated anti-HIV antibody, or antigen binding portion thereof, comprising at least one complementarity determining region (CDR) having a sequence selected from the group consisting of SEQ ID NOs: 33-38. |
| 地址 |
New York NY US |
