| 发明名称 |
METHODS FOR OVERCOMING GLUTAMINE DEPRIVATION DURING MAMMALIAN CELL CULTURE |
| 摘要 |
<p>The present invention pertains to methods of producing polypeptide of interest in cell cultures lacking glutamine. The present invention further pertains to a method of producing a protein of interest in a large scale cell culture, comprising supplementing the cell culture with nucleic acid synthesis precursors and/or corticosteroids.</p> |
| 申请公布号 |
WO2015148515(A1) |
申请公布日期 |
2015.10.01 |
| 申请号 |
WO2015US22259 |
申请日期 |
2015.03.24 |
| 申请人 |
BIOGEN MA INC. |
发明人 |
YANG, WILLIAM;HUANG, YAO-MING;MARTY, SINACORE;RYLL, THOMAS;LU, JIUYI |
| 分类号 |
C12N5/00 |
主分类号 |
C12N5/00 |
| 代理机构 |
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