发明名称 |
Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
摘要 |
<p>ANTIGEN-BINDING MOLECULE CAPABLE OF BINDING TO TWO OR MORE ANTIGEN MOLECULES REPEATEDLY It is found that a molecule of an antibody which exhibits a weaker antigen-binding activity at a p11 value in an early endosome compared with that at a p11 value in a plasma can bind to two or more antigen molecules, and it is also found that the antibody has a long half-life in a plasma and is improved in the period during which the antibody can bind to an antigen.</p> |
申请公布号 |
AU2015227424(A1) |
申请公布日期 |
2015.10.01 |
申请号 |
AU20150227424 |
申请日期 |
2015.09.16 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
MAEDA, ATSUHIKO;IGAWA, TOMOYUKI;NAKAI, TAKASHI;ISHII, SHINYA |
分类号 |
C07K16/28;A61K39/395;C12P21/08;G01N33/15;G01N33/50 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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