MR Imaging Apparatus And Method For Generating A Perfusion Image With Motion Correction

摘要

A magnetic resonance method and system are provided for generating real-time motion-corrected perfusion images based on pulsed arterial spin labeling (PASL) with a readout sequence such as a 3D gradient and spin echo (GRASE) image data acquisition block. The real-time motion correction is achieved by using a volumetric 3D EPI navigator that is provided during an intrinsic delay in the PASL sequence, which corrects for motion prospectively and does not extend the image data acquisition time as compared to a similar non-motion-corrected imaging procedure.

主权项

1. An MR imaging system for generating a real-time motion-corrected magnetic resonance perfusion image of a region of interest, comprising:
an RF (Radio Frequency) signal generator and a magnetic field gradient generator configured to provide an RF pulse and magnetic field gradient sequence for acquisition of MR image data, said RF pulse and magnetic field gradient sequence comprising:
a pulse sequence for selectively tagging blood protons in a volume upstream of the region of interest, the pulse sequence comprising:
a pre-saturation pulse;at least one of an adiabatic tagging pulse or an adiabatic control pulse;a first delay followed by a plurality of periodic saturation pulses;a first background suppression pulse provided at least one of during and directly after the plurality of periodic suppression pulses;a second background suppression pulse provided after the plurality of periodic suppression pulses;a second delay sufficient to allow the tagged blood protons to flow into the region of interest; andan outer volume suppression pulse;a 3D volume navigator following said plurality of periodic suppression pulses and at least one of directly preceding or directly following the second background suppression pulse; anda readout sequence for acquiring RF image data for the region of interest, and an image processing unit configured to:
generate motion-corrected images based on the RF image data and the 3D volume navigator data; andgenerate a perfusion image by subtracting a first image based on a first set of RF image data obtained using the adiabatic control pulse from a second image based on a second set of RF image data obtained using the adiabatic tagging pulse.