| 发明名称 |
METHOD FOR PREVENTING REDUCTION OF POLYPEPTIDE BY ADDING AMINO ACID TO CULTURE SOLUTION |
| 摘要 |
The present invention provides a method for preventing the reduction of a desired polypeptide during purification in order to purify the polypeptide in high yield from a culture solution which contains recombinant host cells and the polypeptide. |
| 申请公布号 |
US2015275259(A1) |
申请公布日期 |
2015.10.01 |
| 申请号 |
US201314432958 |
申请日期 |
2013.10.03 |
| 申请人 |
KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
Inoue Hidetoshi |
| 分类号 |
C12P21/00;C07K16/00 |
主分类号 |
C12P21/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for preventing the reduction of a polypeptide expressed in recombinant host cells and secreted in a culture solution, comprising adding an amino acid to the culture solution. |
| 地址 |
Tokyo JP |
