| 摘要 |
<p>The present invention is directed to a bicyclic heteroaryl benzamide compounds of formula (I) which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.</p> |
| 申请人 |
MERCK SHARP & DOHME CORP.;MITCHELL, HELEN;FRALEY, MARK, E.;COOKE, ANDREW, J.;STUMP, CRAIG, A.;CHEN, YI HENG;BESHORE, DOUGLAS, C.;ZHANG, XU-FANG;MCCOMAS, CASEY, C.;SCHIRRIPA, KATHY;MCWHERTER, MELODY;MERCER, SWATI, P.;MOORE, KEITH, P.;LIU, PING;WOOD, HAROLD, B.;LI, CHUN SING;MAO, QINGHUA |
发明人 |
MITCHELL, HELEN;FRALEY, MARK, E.;COOKE, ANDREW, J.;STUMP, CRAIG, A.;CHEN, YI HENG;BESHORE, DOUGLAS, C.;ZHANG, XU-FANG;MCCOMAS, CASEY, C.;SCHIRRIPA, KATHY;MCWHERTER, MELODY;MERCER, SWATI, P.;MOORE, KEITH, P.;LIU, PING;WOOD, HAROLD, B.;LI, CHUN SING;MAO, QINGHUA |
