摘要 |
PROBLEM TO BE SOLVED: To provide methods for the production of interferon-βpolypeptides by bacterial cells. SOLUTION: In the method for the production of interferon-βpolypeptides by bacterial cells, cells capable of producing IFN-βpolypeptide are cultured under conditions that induce increased production of IFN-βpolypeptide. Such conditions include, for example, low potassium cation concentration and/or very low sodium cation concentration and/or specific pH ranges. COPYRIGHT: (C)2008,JPO&INPIT
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