AN IMPROVED MOLECULAR DIAGNOSTIC AND COMPUTERIZED DECISION SUPPORT SYSTEM INCORPORATING BIOINFORMATIC SOFTWARE FOR SELECTING THE OPTIMUM TREATMENT FOR HUMAN CANCER

摘要

A computerized decision support system and method for predicting which of one or more drugs suitable to treat a cancerous condition in a patient are the optimum drug(s), where such selection is based upon the particular patient' s genotype. A PCR kit and/or a gene chip detects multiple genes, expressions and/or mutations associated with a particular cancer using a sample of the patient's tissue or blood. A detector accepts the gene chip and analyzes the patient's genotype; and a computerized system utilizing a gene expression cutoff point uses a database which associates patient genotypes and the efficacy and toxicity of various anti-cancer drugs used in treating patients with a particular cancerous condition connected to the detector to correlate the output of the detector to the database to provide a definitive recommendation as to which drug or drugs are optimum for treating the patient's cancer.