发明名称 |
N-DIHYDROXYALKYL-SUBSTITUTED 2-OXOIMIDAZOLE DERIVATIVE |
摘要 |
It is intended to provide a compound represented by the formula (I) (I) (wherein R represents an alkyl group having 1 to 6 carbon atoms substituted with 2 hydroxyl groups, Cy represents a bicyclic or tricyclic aliphatic carbocyclic group having 6 to 10 carbon atoms which may have a substituent in some cases). The compound acts as a nociceptin receptor antagonist and is useful as, for example, a narcotic analgesic resistance reversal agent; a reversal agent for narcotic analgesic dependency or withdrawal syndrome; an analgesic action enhancing agent; an anti-obesity agent or an appetite control agent; an improving agent or preventive agent for decline in learning and memory abilities or dementia symptom; an improving agent for cognitive function in the developmental stage; a therapeutic agent for schizophrenia; a therapeutic agent for regressive neurodegenerative disease; an antidepressant agent or an emotion control agent; a therapeutic agent or preventive agent for diabetes insipidus; a therapeutic agent or preventive agent for polyuria; a therapeutic agent for hypopiesis and the like.
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申请公布号 |
KR20080033262(A) |
申请公布日期 |
2008.04.16 |
申请号 |
KR20087000923 |
申请日期 |
2008.01.11 |
申请人 |
BANYU PHARMACEUTICAL CO., LTD. |
发明人 |
HASHIMOTO MASAYA;IWASAWA YOSHIKAZU;KAWAMOTO HIROSHI;OHTA HISASHI;OZAKI SATOSHI;SAGARA TAKESHI;SAKOH HIROKI;SATOH ATSUSHI |
分类号 |
C07D401/04;A61K31/454 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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