Modified bio-related substance, process for producing the same, and intermediate

摘要

Provided is a compound represented by the following formula (2) :
wherein R is a hydrocarbon group having 1 to 24 carbon atoms, the different R groups in the compound being the same or different from each other; OA 1 and OA 2 are oxyalkylene groups, n and m (which are each average numbers of moles of oxyalkylene groups) are respectively 1 to 1000 and 10 to 1000; and X represents a functional group capable of chemically reacting with an unmodified bio-related substance. The above compound is prepared by modifying the hydroxyl group of the following compound (p):
wherein R, OA 1 , OA 2 , n and m are the same as defined above, and the polydispersity Mw/Mn of compound (p) in all the peaks from the starting point of elution to the end point of elution satisfies the relationship Mw/Mn ‰ 1.07 in gel permeation chromatography