发明名称 |
NOVEL PHYSIOLOGICAL SUBSTANCE NESFATIN, SUBSTANCE RELEVANT THERETO, AND USE OF THE SUBSTANCES |
摘要 |
The present invention relates to a novel method of obtaining a factor involved in appetite control and/or body weight control, as well as genes obtained by said method, polypeptides encoded by said genes, or novel polypeptides obtained from the information on polypeptides encoded by said genes as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control. Also the present invention relates to substances that inhibit the effects of said genes or said polypeptides as a means for treating, controlling or diagnosing diseases associated with appetite control and/or body weight control. By using thiazolidine diones having a PPAR³ agonist activity, genes and polypeptides involved in appetite regulation and/or body weight reduction can be obtained. NESFATIN or the like obtained by said method can be used as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control. |
申请公布号 |
EP1900813(A1) |
申请公布日期 |
2008.03.19 |
申请号 |
EP20060780673 |
申请日期 |
2006.06.23 |
申请人 |
TEIJIN PHARMA LIMITED;NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY |
发明人 |
MORI, MASATOMO;SHIMIZU, HIROYUKI;EGUCHI, HIROSHI;YAMAMOTO, MASANORI |
分类号 |
C07K16/18;A61K38/16;A61K38/18;A61K48/00;C07K14/47;C12N15/113;C12Q1/68;G01N33/68 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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