| 摘要 |
<P>PROBLEM TO BE SOLVED: To reduce false signals, caused by the electrochemical conversion of even an unreacted nucleotide 5'-triphosphate derivative that remains in a solution on an electrode in an electrochemical decoding device of DNA base sequences. <P>SOLUTION: The constitution of a polymerase-fixed electrode, comprising both an electrically conductive substrate and a polymerase unit fixed to a surface of the electrically conductive substrate, is to be constituted uses a polymerase unit which comprises a polymerase part; an anchor part; and an electrically conducive part, and in which the polymerase part; the anchor part; and the electrically conducive part are constituted by connecting (1) the polymerase part; the anchor part; and the electrically conducive part, in this order, or (2) the polymerase part; the electrically conductive part; and the anchor part, in this order. The polymerase unit is fixed to the electrically conducive substrate by the anchor part, and the end part of the electrically conducive part on the side that is not fixed to the electrically conducive substrate is positioned to the vicinity of an active section of the polymerase part. <P>COPYRIGHT: (C)2008,JPO&INPIT |
