发明名称 |
ASSAY FOR THE DIAGNOSIS OF ALZHEIMER'S DISEASE BASED ON THE DETERMINATION OF THE RATIO OF GAMMA-SECRETASE ABETA CLEAVAGE PRODUCTS |
摘要 |
Described is a method for the diagnosis of Alzheimer's disease (AD) or a particular stage of the disease which is based on the determination of the ratio of at least two gamma-secretase cleavage products, Abeta48, Abeta45, Abeta42, Abeta38 and Abeta35, preferably the ratio of Abeta38: Abeta42. A decreased ratio of Abeta38: Abeta42 as compared to the normal ratio is indicative of AD. Moreover, kits suitable for carrying out said diagnostic method are described. |
申请公布号 |
WO2007140843(A2) |
申请公布日期 |
2007.12.13 |
申请号 |
WO2007EP03505 |
申请日期 |
2007.04.20 |
申请人 |
FU BERLIN;MULTHAUP, GERD;MUENTER, LISA-MARIE |
发明人 |
MULTHAUP, GERD;MUENTER, LISA-MARIE |
分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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