发明名称 TREATMENT OF PAIN DISORDERS WITH TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENAMINE AND ITS FORMAMIDE
摘要 Treatment of pain disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2 ,3,4-tetrahydro-1-naphthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)- 1,2,3,4-tetrahydro-1-naphthalenamine is disclosed. A process for preparing 4 -(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine is also disclosed . The process includes the preparation of all four isomers of N-[4-(3,4-dich lorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also usef ul in treatment of pain disorders.
申请公布号 CA2653498(A1) 申请公布日期 2007.12.13
申请号 CA20072653498 申请日期 2007.03.30
申请人 SEPRACOR INC. 发明人 TARANTINO, PAUL;CAMPBELL, UNA;BUSH, LARRY
分类号 A61P25/00;A61P25/06 主分类号 A61P25/00
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