| 摘要 |
<p>A process for the preparation of substituted benzothiazinoindoles of general formula (I) wherein R1, R2, and R 4 are independently selected from hydrogen, chloro, fluoro, amino, nitro, cyano, CHO, (C1-C3)alkyl, perhalo(C l-C3)alkyl, (C1-C3)alkoxy, aryl, aralkyl, aralkoxy, (C5-C7)heterocyclyl, (C 5-C7)heterocyclylalkyl, (C5-C7) heterocyclyloxy, acyl, acetyl, alkylamino, aminoalkyl, amide, hydroxyalkyl, carboxylic acid and its derivatives, while R3 is selected hydrogen, (C1-C3)alkyl, aryl and carboxylic acid and its derivatives is disclosed, said process comprising cyclization of compound of general formula-II, (i.e. substituted 1-benzenesulfonyl-7-bromo-lH-indole), formula (II) wherein R1, R2, R3 and R4 using suitable catalyst and solvents wherein.</p> |
