摘要 |
The invention provides novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies where the compounds have the general formula (I): wherein Q, X<SUB>1</SUB>, X<SUB>2</SUB>, Y, Z<SUB>1</SUB>, Z<SUB>2</SUB>, Z<SUB>3</SUB>, Z<SUB>4</SUB>, R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>3'</SUB>, R4, R<SUB>4',</SUB> R<SUB>5</SUB>, R<SUB>6</SUB>, R<SUB>6'</SUB> and n are as described herein. |
申请人 |
GENENTECH, INC.;KOEHLER, MICHAEL F. T.;GAZZARD, LEWIS, J.;TSUI, VICKIE HSIAO-WEI |
发明人 |
KOEHLER, MICHAEL F. T.;GAZZARD, LEWIS, J.;TSUI, VICKIE HSIAO-WEI |