发明名称 |
METHOD OF PREPARING SAMPLE FOR MALDI MASS SPECTROMETRY AND REAGENT COMPOSITION THEREFOR |
摘要 |
<p>A simple and efficient method of preparing a sample in the measurement according to matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) capable of inhibiting any ion suppression by impurities, such as inorganic salts and surfactants, contained in the sample. An analyte and matrix molecules are co-crystallized in the presence of porous microparticles. Preferably, this co-crystallization is carried out by bringing the analyte, matrix molecules and porous microparticles into contact with each other on a target plate and thereafter drying the mixture. The porous microparticles consist of an ion exchanger having an average particle diameter of not more than 50 µm, preferably a strongly basic anion exchanger.</p> |
申请公布号 |
EP1835282(A1) |
申请公布日期 |
2007.09.19 |
申请号 |
EP20060701964 |
申请日期 |
2006.01.04 |
申请人 |
RIKEN |
发明人 |
HIROTA, HIROSHI;ASANUMA, MIWAKO;FUKUZAWA, SEKETSU;YOKOYAMA, SHIGEYUKI |
分类号 |
H01J49/16;G01N33/68;H01J49/00 |
主分类号 |
H01J49/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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