NITROGENATED HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

摘要

Disclosed are: a novel compound having a xanthine oxidase inhibitory activity and an uric acid excretion promoting activity; and a pharmaceutical composition comprising the compound as an active ingredient. The compound is a nitrogenated heterocyclic compound represented by the general formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein Y<SUP>1</SUP> represents N or C(R<SUP>4</SUP>); Y<SUP>2</SUP> represents N or C(R<SUP>5</SUP>); R<SUP>4</SUP> and R<SUP>5</SUP> independently represent an alkyl group, a hydrogen atom or the like; one of R<SUP>1</SUP> and R<SUP>2</SUP> represents an aryl group which may be substituted, an alkoxy group or a heterocyclic group which may be substituted, and the other of R<SUP>1</SUP> and R<SUP>2</SUP> represents a haloalkyl group, a cyano group, a halogen atom or the like; and R<SUP>3</SUP> represents a 5-tetrazolyl group or a carboxy group.