| 发明名称 |
PYRIDOPYRIMIDINONE INHIBITORS OF PIM-1 AND/OR PIM-3 |
| 摘要 |
Compounds of formula I, useful for inhibiting PIM-I and/or PIM-3: and pharmaceutically acceptable salts thereof, wherein Y, Z, R<SUB>1</SUB>, R<SUB>3</SUB>, Q, X and R<SUB>4</SUB> are as defined above. Pharmaceutical compositions and methods of treating diseases and conditions, such as cancer, are also disclosed. |
| 申请公布号 |
WO2007044724(A2) |
申请公布日期 |
2007.04.19 |
| 申请号 |
WO2006US39568 |
申请日期 |
2006.10.05 |
| 申请人 |
EXELIXIS, INC.;KEARNEY, PATRICK;BROWN, SAMUEL, DAVID;KOLTUN, ELENA, S. |
发明人 |
KEARNEY, PATRICK;BROWN, SAMUEL, DAVID;KOLTUN, ELENA, S. |
| 分类号 |
C07D213/81;C07D257/04;C07D307/68;C07D307/93;C07D333/38 |
主分类号 |
C07D213/81 |
| 代理机构 |
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