CHEMICAL COMPOUNDS

摘要

Compounds of formula (Ia) are found to be active in inhibiting replication of flaviviridae viruses (Ia), wherein R<SUB>1</SUB> and R<SUB>2</SUB> are the same or different and represent hydrogen, halogen, -L-O-R<SUB>3</SUB>, -L-O-L-A or -L-O-L´-A´, wherein each L is the same or different and represents a direct bond or a C<SUB>1</SUB>-C<SUB>4</SUB> alkylene group; L´ represents a direct bond or a C<SUB>2</SUB>-C<SUB>4</SUB> alkylene group; R<SUB>3</SUB> represents hydrogen, C<SUB>1</SUB>-C<SUB>4</SUB> alkyl or C<SUB>1</SUB>-C<SUB>4</SUB> haloalkyl; A represents a 5- to 10-membered heterocyclyl group; and A´ represents a C<SUB>6</SUB>-C<SUB>1</SUB> aryl group; wherein at least one of R<SUB>1</SUB> and R<SUB>2</SUB> is -L-O-R<SUB>3</SUB>, -L-O-L-A or -L-O-L´-A´.