摘要 |
<p>A method of detecting the presence or absence of an analyte in a sample uses an analyte carrier with a calibration dye held in a region near a metal surface. A reporter dye is held away from a region near the metal surface and is displaceably attached to a selective agent. The selective agent is capable of binding to an analyte so that when the analyte binds to the selective agent the reporter dye detaches and moves to a region near a metal surface. The difference in response to illumination from the reporter dye and calibration dye can be used to detect the presence, amount or absence of an analyte sample.</p> |