An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcgR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.
申请公布号
CA2625998(A1)
申请公布日期
2007.04.19
申请号
CA20062625998
申请日期
2006.10.06
申请人
XENCOR, INC.
发明人
CHEN, BAO-LU;KARKI, SHER BAHADUR;HAMMOND, PHILIP W.;LAZAR, GREGORY ALAN;CHU, SEUNG Y.;CARMICHAEL, DAVID F.;DESJARLAIS, JOHN R.;KUNKEL, LORI
