| 发明名称 |
Azetidines as MEK inhibitors for the treatment of proliferative diseases |
| 摘要 |
<p>Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.</p> |
| 申请公布号 |
AU2006302415(A1) |
申请公布日期 |
2007.04.19 |
| 申请号 |
AU20060302415 |
申请日期 |
2006.10.05 |
| 申请人 |
EXELIXIS, INC. |
发明人 |
JEFFRY KIMO CURTIS;KENNETH D. RICE;CHARLES M. BLAZEY;SIMONA COSTANZO;ABIGAIL R. KENNEDY;CSABA J. PETO;TSZE H. TSANG;ELENA KOLTUN;STEVEN CHARLES DEFINA;LARISA DUBENKO;NAING AAY;NEEL KUMAR ANAND;JEAN-CLAIRE LIMUN MANALO;OWEN JOSEPH BOWLES;ANGIE INYOUNG KIM;ANAGHA ABHIJIT JOSHI;JOERG BUSSENIUS |
| 分类号 |
C07D205/04;C07D205/06;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D403/06;C07D403/12;C07D405/12;C07D409/06;C07D409/12;C07D413/12;C07D413/14;C07D417/12;C07D471/04 |
主分类号 |
C07D205/04 |
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