发明名称 |
PROCESS FOR PREPARING ORAL CALCIUM COMPOSITIONS |
摘要 |
The invention provides a process for the preparation of an orally administrable calcium composition, said process comprising the steps of: (i) obtaining a physiologically tolerable particulate calcium compound having a mean particle size in the range 3 to 40µm, having a crystalline structure and having a surface area of 0.1 to 1.2 m 2 /g; (ii) mixing said calcium compound with a water-soluble diluent and an aqueous solution of a water soluble binder in a fluid bed granulation apparatus and drying the resulting mixture to produce a first granulate; (iii) optionally mixing said first granulate with one or more further components to produce a second granulate; and (iv) optionally compressing said first or second granulate to form tablets. |
申请公布号 |
PT1128815(E) |
申请公布日期 |
2007.01.31 |
申请号 |
PT19990952710T |
申请日期 |
1999.11.05 |
申请人 |
NYCOMED PHARMA AS |
发明人 |
JAN YNGVAR PIENE;DINA DOGGER SCHMIDT |
分类号 |
A23L1/304;A61K9/16;A61K9/20;A61K31/122;A61K31/352;A61K31/375;A61K31/4415;A61K31/59;A61K33/06;A61K47/12;A61K47/26;A61K47/32;A61K47/36;A61K47/38;A61P19/10 |
主分类号 |
A23L1/304 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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