| 发明名称 |
CYCLOOXYGENASE-2 INHIBITOR COMPOSITIONS HAVING RAPID ONSET OF THERAPEUTIC EFFECT |
| 摘要 |
PHARMACEUTICAL COMPOSITIONS ARE PROVIDED COMPRISING ONE OR MORE ORALLY DELIVERABLE DOSE UNITS, EACH COMPRISING A SELECTIVE CYCLOOXYGENASE-2 INHIBITORY DRUG OF LOW WATER SOLUBILITY IN A THERAPEUTICALLY EFFECTIVE AMOUNT, WHEREIN THE DRUG IS PRESENT IN THE FORM OF SOLID PARTICLES, ABOUT 25TO 100BY WEIGHT OF WHICH ARE SMALLER THAN 1 µM. THE COMPOSITIONS ARE USEFUL IN TREATMENT OF PROPHYLAXIS OF CYCLOOXYGENASE-2 MEDIATED CONDITIONS AND DISORDERS AND HAVE PARTICULAR ADVANTAGES WHERE RAPID ONSET OF THERAPEUTIC EFFECT IS DESIRED.
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| 申请公布号 |
MY128366(A) |
申请公布日期 |
2007.01.31 |
| 申请号 |
MYPI20005733 |
申请日期 |
2000.12.06 |
| 申请人 |
PHARMACIA CORPORATION |
发明人 |
TUGRUL T. KARARLI;MARK J. KONTNY;SUBBASH DESAI;MICHAEL J. HAGEMAN;ROYAL J. HASKELL |
| 分类号 |
A61K31/32;C07D233/60;A61K9/14;A61K9/20;A61K9/24;A61K9/26;A61K9/48;A61K9/50;A61K31/34;A61K31/341;A61K31/352;A61K31/41;A61K31/415;A61K31/42;A61K31/44;A61K31/444;A61K45/00;A61K45/06;A61P1/00;A61P1/02;A61P1/04;A61P1/16;A61P3/10;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P15/00;A61P15/04;A61P17/00;A61P17/02;A61P17/06;A61P17/10;A61P19/02;A61P19/10;A61P21/00;A61P21/04;A61P25/00;A61P25/06;A61P25/28;A61P25/32;A61P27/02;A61P27/12;A61P29/00;A61P31/12;A61P31/18;A61P35/00;A61P37/08;A61P43/00;C07D213/61;C07D231/12;C07D261/08;C07D307/58;C07D311/58 |
主分类号 |
A61K31/32 |
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