| 发明名称 |
Recombinant alpha-L-iduronidase, methods for producing and purifying the same and methods for treating diseases caused by deficiencies thereof |
| 摘要 |
The present invention provides a recombinant alpha-L-iduronidase and biologically active fragments and mutants thereof, methods to produce and purify this enzyme as well as methods to treat certain genetic disorders including-alpha-L-iduronidase deficiency and mucopolysaccharidosis I (MPS 1).
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| 申请公布号 |
US2006286087(A1) |
申请公布日期 |
2006.12.21 |
| 申请号 |
US20060429422 |
申请日期 |
2006.05.05 |
| 申请人 |
BIOMARIN PHARMACEUTICAL INC. |
发明人 |
KAKKIS EMIL D.;TANAMACHI BECKY |
| 分类号 |
A61K38/47;C12N15/09;A61K9/08;A61K38/00;A61K38/43;A61K47/02;A61K47/10;A61K48/00;A61P3/00;A61P19/00;A61P43/00;C07H21/04;C12N9/24;C12N9/36;C12N9/88;C12P21/06 |
主分类号 |
A61K38/47 |
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