| 摘要 |
<p>The present invention relates to compositions and methods for treating Staphylococcus aureus ( S. aureus ) infections. In particular, the present invention provides vaccines comprising a Panton-Valentine Leukocidin (PVL) antigen, antibodies which bind a PVL antigen and compositions containing the same, methods of making such compositions and methods for treating S . aureus infections, including those that are community acquired methicillin-resistant infections. The present invention also provides PVL antibodies, including PVL antibodies specific for a single PVL subunit, and PVL antigens, including conjugated and mutated PVL antigens.</p> |
