发明名称 Antibodies against biotinylated histones and related proteins and assays related thereto
摘要 Described are specific biotinylation sites in histones, polypeptide fragments of histones comprising such biotinylation sites, and antibodies that selectively bind to such biotinylated sites. Also described are methods to detect biotinylation in a sample, to detect biotinyl transferase activity in a sample, to identify regulators of biotinylation, and to detect activities associated with histone biotinylation. Also described is an assay to detect or measure histone debiotinylation.
申请公布号 US2006286611(A1) 申请公布日期 2006.12.21
申请号 US20050173982 申请日期 2005.06.30
申请人 BOARD OF REGENTS OF UNIVERSITY OF NEBRASKA 发明人 ZEMPLENI JANOS;SARATH GAUTAM
分类号 G01N33/574;C07K16/40;G01N33/53 主分类号 G01N33/574
代理机构 代理人
主权项
地址