METHODS AND COMPOSITIONS FOR ENHANCEMENT OF IMMUNITY BY IN VIVO DEPLETION OF IMMUNOSUPPRESSIVE CELL ACTIVITY

摘要

The present invention provides a method of enhancing an immune response in a subject, comprising administering to the subject a reagent that targets a cell having immunosuppressive activity, in an amount effective in reducing the immunosuppressive activity of the cell, thereby enhancing an immune response in the subject. Also provided are methods of treating cancer and infection in a subject by administering the reagents of this invention to a subject.