| 摘要 |
<p>The present invention relates to compounds comprising an oxazole or thiazole moiety of formula (I), processes for preparing them, pharmaceutical compositions comprising said compounds and their uses as H<SUB>3</SUB> -receptor ligands, Formula (I), wherein , A<SUP>1</SUP> is CH, C(alkyl), C-halogen or N; R<SUP>l</SUP> is hydrogen, halogen, C<SUB>1-6 </SUB>alkyl or alkoxy; R<SUP>2</SUP> is, Formula (II'), A<SUP>3</SUP> is O or S; R<SUP>3</SUP> is hydrogen, halogen, C<SUB>1-6 </SUB>alkyl or alkoxy; R<SUP>4</SUP> is hydrogen, halogen, C<SUB>1-6 </SUB>alkyl, alkoxy or -O-L; R<SUP>5</SUP> is hydrogen or -O-L, wherein L is an aminoalkyl group and at least one of R<SUP>4</SUP> and R<SUP>5</SUP> should be -O-L.</p> |
