发明名称 |
STAPHYLOCOCCUS AUREUS ISD PROTEIN-BASED ANTI-INFECTIVES |
摘要 |
Iron-regulated surface determinant proteins IsdA, IsdB and IsdC from Staphylococcus aureus, as well as antibodies, antisense nucleic acids and siRNA specific to IsdA, IsdB or IsdC are used as vaccines and in method for treating or preventing a disease or condition associated with S. aureus infections Screening assays for identifying agents that inhibit or interfere with the expression level and/or function of IsdA, IsdB or IsdC are also described. |
申请公布号 |
WO2006059247(A3) |
申请公布日期 |
2006.10.05 |
申请号 |
WO2005IB04126 |
申请日期 |
2005.10.25 |
申请人 |
THE UNIVERSITY OF WESTERN ONTARIO;HEINRICHS, DAVID, E.;VERMEIREN, CHRISTIE |
发明人 |
HEINRICHS, DAVID, E.;VERMEIREN, CHRISTIE |
分类号 |
A61K39/40;A61K31/7088;A61K39/085;A61K39/395;A61P31/04;C12Q1/14;C12Q1/18;C12Q1/68 |
主分类号 |
A61K39/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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