发明名称 |
Novel MHC class II restricted T cell epitopes from the cancer antigen, NY ESO-1 |
摘要 |
The present invention discloses the identification and isolation of novel MHC class II epitopes derived from the cancer antigen, NY ESO-1. The novel MHC class II epitopes from NY-EsO-1 are recognized by CD4 + T lymphocytes in an HLA class II restricted manner, in particular HLA-DR or HLA-DP restricted. The products of the gene are promising candidates for immunotherapeutic strategies for the prevention, treatment and diagnosis of patients with cancer. |
申请公布号 |
AU785151(B2) |
申请公布日期 |
2006.10.05 |
申请号 |
AU20010033062 |
申请日期 |
2001.01.26 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
RONG-FU WANG;STEVEN A ROSENBERG;GANG ZENG |
分类号 |
C12N15/09;C12N15/12;A61K35/14;A61K35/76;A61K38/00;A61K39/00;A61K39/39;A61K39/395;A61K45/00;A61K48/00;A61P35/00;C07K14/47;C07K14/82;C07K16/30;C07K16/32;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/06;C12N5/10;C12N7/00;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;C12R1/91 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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