| 发明名称 |
Capsaicin receptor agonists |
| 摘要 |
Capsaicin receptor agonists are provided. Such compounds are ligands that may be used to modulate VR1 activity in vivo or in vitro, and are particularly useful in the treatment of conditions responsive to capsaicin receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.
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| 申请公布号 |
US2006194805(A1) |
申请公布日期 |
2006.08.31 |
| 申请号 |
US20060412526 |
申请日期 |
2006.04.26 |
| 申请人 |
NEUROGEN CORPORATION |
发明人 |
BAKTHAVATCHALAM RAJAGOPAL;BLUM CHARLES A.;BRIELMANN HARRY;CALDWELL TIMOTHY M.;CORTRIGHT DANIEL N.;HODGETTS KEVIN J.;PETERSON JOHN M.;ZHENG XIAOZHANG |
| 分类号 |
A61K31/525;A61K31/498;A61K31/517;A61K31/519;C07D213/56;C07D215/44;C07D235/14;C07D239/94;C07D401/12;C07D409/12;C07D417/12;C07D471/04;C07D475/04;C07D475/06;C07D475/10;C07D487/02 |
主分类号 |
A61K31/525 |
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