发明名称 |
MEDICAMENTS FOR ALZHEIMER |
摘要 |
<p>Novel multifunctional compound for the treatment or the retardation of neurodegenerative diseases e.g. Alzheimer's disease and related pathological conditions. Formula (I); wherein, R is a non-steroidal anti-inflammatory drug moiety, being selected from the category of acetic acid derivatives (such as indomethacin), propionic acid derivatives (e.g. naproxen, ketoprofen) or various other acids with anti-inflammatory action which do not belong to the Above mentioned categories, A is a CHOH group or a CH<SUB>2</SUB> group or a (CH<SUB>2</SUB>)<SUB>2</SUB> group, Y is an antioxidant moiety (cysteamine or cysteine ethyl ester) or neuroprotective moiety (2-Pyridin-3-yl-alkanol) or NGF-inducing moiety (e.g. 2-methoxy-4-methyl-phenol).</p> |
申请公布号 |
WO2006090192(A1) |
申请公布日期 |
2006.08.31 |
申请号 |
WO2005GR00005 |
申请日期 |
2005.02.28 |
申请人 |
TSETI, IOULIA;KOUROUNAKIS, PANOS;DOULGKERIS, CHRISTOS;GALANAKIS, DIMITRIOS;KOUROUNAKIS, ANGELIKI |
发明人 |
KOUROUNAKIS, PANOS;DOULGKERIS, CHRISTOS;GALANAKIS, DIMITRIOS;KOUROUNAKIS, ANGELIKI |
分类号 |
C07D403/06;A61K31/405;A61K31/445;C07D207/16;C07D211/60 |
主分类号 |
C07D403/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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