发明名称 PYRIDYL ACETIC ACID COMPOUNDS
摘要 <p>The present invention provides a compound represented by the formula (I): wherein R&lt;SUB&gt;1&lt;/SUB&gt; is a C?1-6#191 alkyl group optionally substituted by a C?3-10#191 cycloalkyl group, R&lt;SUB&gt;2&lt;/SUB&gt; is a C?2-6#191 alkyl group, R&lt;SUB&gt;3&lt;/SUB&gt; is a hydrogen atom, a C?1-6#191 alkyl group or a halogen atom, and X is -OR&lt;SUB&gt;6&lt;/SUB&gt; or -NR&lt;SUB&gt;4&lt;/SUB&gt;R&lt;SUB&gt;5&lt;/SUB&gt; wherein R&lt;SUB&gt;4&lt;/SUB&gt; and R&lt;SUB&gt;6&lt;/SUB&gt; are each independently a hydrogen atom, an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, R&lt;SUB&gt;5&lt;/SUB&gt; is an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group or an optionally substituted hydroxy group, or R&lt;SUB&gt;4&lt;/SUB&gt; and R&lt;SUB&gt;5&lt;/SUB&gt; optionally form, together with the adjacent nitrogen atom, an optionally substituted nitrogen-containing heterocycle, or a salt thereof. The compound of the present invention has a superior peptidase inhibitory action and is useful as an agent for the prophylaxis or treatment of diabetes and the like.</p>
申请公布号 WO2006090915(A1) 申请公布日期 2006.08.31
申请号 WO2006JP304177 申请日期 2006.02.24
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED;MAEZAKI, HIRONOBU;SUZUKI, NOBUHIRO 发明人 MAEZAKI, HIRONOBU;SUZUKI, NOBUHIRO
分类号 C07D213/55;A61K31/44;A61K31/4427;A61P3/08;C07D213/56;C07D401/12;C07D401/14;C07D405/12;C07D409/12;C07D413/12;C07D417/12 主分类号 C07D213/55
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