| 摘要 |
<p>There are provided novel compounds of formula (I) wherein R<img id="custom-character-00001" he="2.46mm" wi="1.44mm" file="US20060035938A1-20060216-P00900.TIF" alt="custom character" img-content="character" img-format="tif"/>1?, R<img id="custom-character-00002" he="2.46mm" wi="1.44mm" file="US20060035938A1-20060216-P00900.TIF" alt="custom character" img-content="character" img-format="tif"/>4?. R<img id="custom-character-00003" he="2.46mm" wi="1.44mm" file="US20060035938A1-20060216-P00900.TIF" alt="custom character" img-content="character" img-format="tif"/>5?, G<img id="custom-character-00004" he="2.46mm" wi="1.44mm" file="US20060035938A1-20060216-P00900.TIF" alt="custom character" img-content="character" img-format="tif"/>1?, G<img id="custom-character-00005" he="2.46mm" wi="1.44mm" file="US20060035938A1-20060216-P00900.TIF" alt="custom character" img-content="character" img-format="tif"/>2?, X, L, Y<img id="custom-character-00006" he="2.46mm" wi="1.44mm" file="US20060035938A1-20060216-P00900.TIF" alt="custom character" img-content="character" img-format="tif"/>1?, Y<img id="custom-character-00007" he="2.46mm" wi="1.44mm" file="US20060035938A1-20060216-P00900.TIF" alt="custom character" img-content="character" img-format="tif"/>2? and n are as defined in the Specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors or neutrophil elastase.</p> |
